"Heart in a Cage" is the second single from The Strokes' third album, First Impressions of Earth released in the UK on 20 March 2006, and worldwide 18 April 2006. The CD1 version of the single featured their cover of Ramones' "Life's a Gas" as a B-side, while the CD2 version featured an early version of the song "You Only Live Once" (previously named "I'll Try Anything Once"), along with the single's music video. The 7" vinyl includes "I'll Try Anything Once", performed by Nick Valensi on the keyboard.